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Caffeine can reduce inflammation in patients with eczema and psoriasis

Adding caffeine to topical skin treatments would be a simple way to reduce inflammation in patients with atopic dermatitis and psoriasis, suggests a review presented at the Psoriasis: From Gene to Clinic International Congress, which took place in London this week.
Dermatology Times – Dermatology

Solutions to Eczema Itching – Relief From Scratching the Rash and Ways to Stop Skin Inflammation

For many people with atopic dermatitis, it is the eczema itching that is the most frustrating aspect. Itching is a constant reminder of a problem. When you itch it disrupts your connection with whatever you are involved with. When I speak with clients with eczema rashes, psoriasis or other skin issues , itching is their constant reminder of something being wrong.

Scratching an itchy skin rash is almost impossible to resist. But when you scratch blisters, red bumps or patches you are making the skin problem worse. We don’t always remember to wash our hands and this can lead to a bacterial infection. Kids are very prone to this. Even if you do wash your hands, when you have an open sore, blister or pimple irritated by scratching, an external agent that comes in contact with the skin can result in an infection.

Reducing the sensation of itching is important for mental health as well. It is hard to concentrate on anything when you have the urge to scratch yourself frequently. This also can make sleeping tough. Without proper rest, you will slow down healing.

Oils such as coconut oil, olive oil and neem oil are all good for the dry eczema skin rash and can give the skin the moisturizer it sorely needs. Clip your nails and your children’s nails plus file them to remove any sharp edges. Using benadryl for sleep is a good way to get the rest needed. People scratch themselves during sleep so having short nails is important. During the day, there are non-drowsy formulas you can take of antihistamines. Oatmeal baths are soothing to the skin. Take a good B-complex capsule as well as multi-vitamin to build your system back to normal.

Though ultimately you need to find the root of the eczema skin problem and not just relieve the itching symptoms, it is important to not scratch the skin. A combination of stress relief, avoidance of problematical foods, awareness of how much sun your body can take and learning environmental triggers is a complete system to relieve the dermatitis problem.

Use a complete system to relieve the itchy eczema rash. Learn how to find Eczema Itching Relief by getting to the root of the rash problem at http://www.itchyskinrash.net/home-remedies-for-eczema.html

More Atopic Dermatitis Articles

Physical activity decreases inflammation linked to psoriatic arthritis

Inflammatory pain is a component of psoriatic arthritis, and participating in physical activity, such as yoga, is a way to reduce inflammation and manage chronic pain if a patient is experiencing it.
Modern medicine – Dermatology Times

Surprise: Th2 cells, inflammation high in both allergic, non-allergic eczema

When I talked to Jon Hanifin last year he mentioned an intriguing fact: eczema comes in two general types. About 80% of atopic eczema patients have allergies and high levels of IgE antibodies. But twenty per cent of patients have eczema without allergies.

The technical term for allergic eczema is “extrinsic” atopic dermatitis; the non-allergic kind is “intrinsic” AD.

Production of IgE—and most antibodies—is activated by type 2 helper T cells. So scientists have generally assumed that extrinsic AD patients had overactive type 2 helper T cells. But new research shows that type 2 helper T cells are overactive in both intrinsic and extrinsic AD patients.

The scientists, led by Emma Guttman-Yassky at Rockefeller University in New York City, analyzed skin and blood samples from 42 extrinsic and 9 intrinsic AD patients, looking at molecular and cellular differences in the immune system and the skin.

They found that type 2 helper T cell activation is actually higher in intrinsic AD patients than extrinsic AD patients. In fact, markers of inflammation in general are higher in intrinsic AD.

Figure 6 from the paper. Scientists now resort to “word clouds” to convey the complexity of molecular biology!

The results are surprising. Patients with intrinsic AD generally do not go on to develop asthma or allergic rhinitis; yet if you just looked at their helper T cells you’d think they were guaranteed to experience even more severe allergies than those suffered by extrinsic AD patients.

So what’s keeping down the IgE levels in intrinsic AD? In the paper, the authors speculate freely, but so far there is no answer.

It also appears that a special class of helper T cells known as type 17 (so-called because they produce the signaling molecule IL-17A) are also more active in intrinsic than extrinsic AD. It’s not clear yet how scientists might  use this knowledge to design therapies more specific than current T cell-suppressing options such as ciclosporin, which can have severe side effects.

The research suggests that future T-cell related therapies will likely be similar for intrinsic and extrinsic AD, despite the different nature of the disease in the two patient groups.

Hat tip to KMO.
End Eczema

Antioxidants fight histamine inflammation

Ripe and tasty blueberries on grey wooden tableResearch tells us that consuming antioxidant foods at every meal helps us stay out of “oxidative debt”. If you’ve been reading my blog and following a similar diet to mine, you’ll be doing this already (and it certainly explains why I can tolerate higher histamine foods). Here’s what we know about how free radicals are causing inflammation generally, and triggering histamine release from mast cells in the body. 

All references always at the end of the post.

It started with a study I tripped over while researching something else: sodium cromoglycate, a commonly prescribed mast cell stabiliser (prevents mast cells from releasing histamine and other inflammation) has antioxidant activity.

Which led me to wondering how histamine and mast cells are linked to antioxidants (the good stuff you find in foods like blueberries).

What I found:

Free radicals (linked to cancer and aging) trigger mast cells into releasing histamine in the body

Anti-oxidant foods can prevent histamine related damage

Polyunsaturated fatty acids (PUFA) are found in walnuts and salmon which both have a good amount of inflammation fighting omega 3 fatty acids. PUFAs are also in sunflower and soybean oil, and meat (unless you go for grass fed and finished), which all have a higher omega 6 content. PUFAs can generate free radicals, which are linked to aging and cancer, and have been found to release histamine from mast cells. This histamine release however is prevented by antioxidant compounds. I’ve been fine with a number of higher histamine foods that have higher omega 3 ratio, this may be why.

Here’s how to create your own histamine balanced healing plan without buying cookbooks or following online food lists. 

According to a recent video by Dr. Michael McGregor, the New York Times best selling author of How Not to Die, antioxidants that fight cancer and prevent age related disease and dementia, are required at every meal, not just once a day. His round up of the latest research really hit home for me since it’s what I’ve been doing for years, only with the intention of balancing out any histamine ingested in that meal. My main source of histamine inflammation preventing antioxidants are fruit and fresh green herbs. I make sure to have a really generous helping of both, every time I eat.

An example would be a few slices of avocado with an antihistamine cilantro, basil and shallot sauce and a generous helping of mixed anti-inflammatory mesclun greens, with a cup of blueberries or other berries/nuts.

People with a mast cell related condition called Mastocytosis are sometimes advised to stay away from morphine and other opiate based medications. I’ve always known it’s because they release histamine from mast cells, but it seems that these medications (and recreational drugs like cocaine) do this by triggering the release of free radicals.

I guess the lesson here is swap out your daily side order of cocaine for fresh basil sauce.

In other news, polyphenols with antioxidant activity were found to have mast cell stabilising properties, which is not news to my readers. It’s the reason I have been taking Dr. Theoharides’ Neuroprotek antioxidant supplement and eating a diet that balances inflammation. I only wish I’d done it sooner than a few years ago!

Here’s a few anti-oxidant foods from Dr. Axe’s website: 

  • Wild blueberries: 14,000 ORAC score.
  • Pecans: 17,000 ORAC score.
  • Artichoke: 9,400 ORAC score.
  • Elderberries: 14,000 ORAC score.
  • Kidney beans: 8,400 ORAC score.
  • Cranberries: 9,500 ORAC score.
  • Oregano, one of the rosmarinic herbs (which include thyme, rosemary and sage) ranks even higher in antioxidant activity than apples (over 40 times higher) and four times higher than blueberries. The Whole Foods website tells us that just one tablespoon of fresh oregano has the same antioxidant activity as an apple.
  • Explains so much to me…

It’s finally here! Man Food – a high nutrient antihistamine and anti-inflammatory ingredient filled book geared towards guys, women who love to work out, yoga like they mean it, or just load up on healing nutrients. Features my personal shopping list of antihistamine and anti-inflammatory foods.

The Anti-cookbook and all liquid Anti-Detox Book, don’t treat any conditions, but feature a plethora of the high nutrient antihistamine and anti-inflammatory ingredients that have been instrumental in helping me feed myself on a limited diet. The Anti-cookbook features a four page list of antihistamine and anti-inflammatory foods and comes in regular and Paleo.

The Low Oxalate Cookbook features antihistamine and anti-inflammatory rich recipes.

Don’t miss the Low Histamine Beauty Survival Guide for non-toxic beauty tips, the skinny on histamine releasing (mast cell degranulating) beauty ingredients, antihistamine and anti-inflammatory beauty alternatives and the top brands natural brands I’ve found.

Take a peek at my other low histamine and antihistamine cookbooks for more high nutrient recipes

——— REFERENCES ———-

Publications, Harvard Health. “The truth about fats: the good, the bad, and the in-between.” Harvard Health. N.p., n.d. Web. 18 Mar. 2017.

Masini, Emanuela, Beatrice Palmerani, Francesco Gambassi, Alessandra Pistelli, Eliana Giannella, Brunella Occupati, Mario Ciuffi, Tatiana Bani Sacchi, and Pier Francesco Mannaioni. “Histamine release from rat mast cells induced by metabolic activation of polyunsaturated fatty acids into free radicals.” Biochemical Pharmacology 39.5 (1990): 879-89. Web.

“The Many Dangers Of Excess PUFA Consumption | Paleo Leap.” Paleo Leap | Paleo diet Recipes & Tips. N.p., 15 Feb. 2016. Web. 18 Mar. 2017.

Greger, M.D. Michael. “Antioxidant-Rich Foods with Every Meal.” NutritionFacts.org. N.p., n.d. Web. 18 Mar. 2017.

“These Foods, Herb, Spices & Oils are Absolutely Bursting with Antioxidants.” Dr. Axe. N.p., 24 Jan. 2017. Web. 18 Mar. 2017.

Bello, M. G. Di, E. Masini, C. Ioannides, J. F. Ndisang, S. Raspanti, T. Bani Sacchi, and P. F. Mannaioni. “Erratum to: Histamine release from rat mast cells induced by the metabolic activation of drugs of abuse into free radicals.” Inflammation Research 62.2 (2012): 247. Web.

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Researchers confirm that inflammation, histamine, cause anxiety (GAD)

It’s hardly news to us those of us with histamine intolerance and mast cell activation that inflammation can cause symptoms of anxiety. Now though, the research has finally caught up, with scientists identifying altered pro and anti-inflammatory profiles in patients with Generalised Anxiety Disorder (GAD). One of the inflammatory agents is monitored in the study can also be released by mast cells (which can also trigger histamine). 

The study published in Brain, Behavior and Immunity provides the first evidence that Generalized Anxiety Disorder (GAD) is associated with an imbalance between interferon (IFN-y), interleukin (IL-10), and tumor necrosis factor (TNF-a), which is released by mast cells.

The authors found that patients with GAD had high levels of pro-inflammatory IFN-y and TNF-a, but low levels of the anti-inflammatory IL-10, compared to healthy control subjects. They believe that an impairment of the tryptophan degrading enzyme leads to degradation of serotonin in patients with GAD.

I’ve long researched the link between histamine, mast cells and anxiety and depression.

You can read about the mast cell-depression link here

And how antihistamines can treat schizophrenia here

Now, with histamine researcher Dr. Janice Joneja once said to me, “Well of course the symptoms are all in the head, histamine is a neurotransmitter!”

You can find my interview with this amazing histamine researcher here

Her comment tickled me immensely given the number of times I was admonished for imagining my symptoms and that it was ridiculous to link what I ate, and how my body felt, to my state of mind.

Read my interview with Harvard trained psychiatrist Dr. Georgia Ede for more on the histamine-mood link

Read all about how histamine can generate symptoms of anxiety here

It seems that us members of the “permanently inflamed tribe” have been vindicated in linking flushing, palpitations, anxiety, tunnel vision and (in my case) a sense of doom almost like an asteroid was on a collision course with my reality, to histamine and inflammation generally.

I was first diagnosed with anxiety at about fourteen years old, but really I’d been suffering from it since childhood. My brother once commented (ok, way more than once), that I was the most fearful and stressed child he’d known (he’s sixteen years older than me). While it’s true that I’ve had a very tumultuous life, growing up in a war zone, father dead at 40 or so, changing schools and moving country every six months at times, I don’t consider that I had a particularly traumatic life compared with many people. And yet I was shaking like a leaf most days, filled with a sense that something truly catastrophic was about to befall me or my loved ones. I would wake up in the morning with a sense of dread, wondering what awful thing was going to happen. It was almost a relief when something would happen, and hopefully I could go about the rest of my day just a smidge less fearful than I started it.

But things got out of hand at university. Within just a few short years I was diagnosed with GAD, bipolar and unipolar depression, borderline personality and was medicated with pretty much everything on the market, for years. Changing my diet allowed me to come off all psychiatric medications (including daily Xanax/benzodiazepines), within a matter of months, but I was still a mess histamine-wise, till I totally overhauled my life.

You can learn how I transitioned from eating a handful of foods to eating a normal diet here (nutrient dense and from scratch is normal to me!).

Nowadays it takes a major life event to properly phase me. What I’m still not great at is dealing with daily anxiety due to a situation beyond my control, like when my mother fell ill last year and I spent a year flying back and forth to a country on another continent.

But I do my best. The meditation and exercise are a huge help, as is knowing that I may be on edge simply because my histamine level might be elevated. And yes, it does still happen to me. Because like you, I’m human, and I’m constantly pushing the boundaries to see what I can get away with.

It’s finally here! Man Food – a high nutrient antihistamine and anti-inflammatory ingredient filled book geared towards guys, women who love to work out, yoga like they mean it, or just load up on healing nutrients. Features my personal shopping list of antihistamine and anti-inflammatory foods.

The Anti-cookbook and all liquid Anti-Detox Book, don’t treat any conditions, but feature a plethora of the high nutrient antihistamine and anti-inflammatory ingredients that have been instrumental in helping me feed myself on a limited diet. The Anti-cookbook features a four page list of antihistamine and anti-inflammatory foods and comes in regular and Paleo.

The Low Oxalate Cookbook features antihistamine and anti-inflammatory rich recipes.

Don’t miss the Low Histamine Beauty Survival Guide for non-toxic beauty tips, the skinny on histamine releasing (mast cell degranulating) beauty ingredients, antihistamine and anti-inflammatory beauty alternatives and the top brands natural brands I’ve found.

Take a peek at my other low histamine and antihistamine cookbooks for more high nutrient recipes

——–REFERENCES——–

Brain Behav Immun. 2017 Feb 1. pii: S0889-1591(17)30021-1. doi: 10.1016/j.bbi.2017.01.021. [Epub ahead of print]

Peripheral inflammatory cytokines and immune balance in Generalised Anxiety Disorder: Case-controlled study.

Hou R1, Garner M2, Holmes C3, Osmond C4, Teeling J5, Lau L3, Baldwin DS6.

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Oxalic Acid Inflammation linked to Histamine, Thyroid Dysfunction & Hashimoto’s

swiss chard bundle on wood table

 

I’ve spoken quite a bit about my experiences dealing with and the link between oxalic acid (found in some of the planet’s healthiest foods) and histamine related inflammation. Today it’s time to examine how a build up of oxalic acid found in low histamine foods like almonds, chard, potatoes, brown rice, millet and others, can not only exacerbate histamine inflammation, but also cause or contribute to thyroid dysfunction and Hashimoto’s. Both conditions are a huge and unfortunately seemingly quite common issue in our histamine intolerance and mast cell activation community. 

Today’s post comes to you via something that popped up in my Facebook feed from the Thyroid Pharmacist Dr. Izabella Wentz. She began looking into the link when she noticed a number of her thyroid patients experiencing oxalic acid symptoms.

I’ve posted a great deal about the effects of oxalic acid found in plant foods: burning urination (in my case feeling like I’m peeing razor blades), needing to pee a lot, general symptoms of interstitial cystitis, pain during intercourse, kidney stones (I didn’t have stones though) and other troubles, and a general increase in histamine type inflammation.

The easiest way to explain how it works inflammation-wise is to use the bucket analogy: our body is a giant bucket and there’s only so much we can put in it before we spill over into symptoms. For example, if we’re exposed to pet dander, stress, intense exercise,  heat or high histamine foods one by one, we may not spill over. Do them all in a day, or a week, and you may experience some uncomfortable inflammation symptoms. But it gets more annoying – let’s say you have too many salicylate rich foods, or histamine foods all at once, you may temporarily experience an inflammatory response (which is nearly identical to, or may actually be histamine related), even if you wouldn’t normally react to salicylate rich or oxalic acid foods. You can read more about all this in my post the Inflammation Bucket and Reacting to Everything? This May Be Why.

Dr. Wentz shared a study that found nearly eighty percent of adults autopsied had oxalate crystals in their thyroid glands. The older they were when they passed, the more likely the find became. A link to Hashimoto’s was made when it was realised that those with this autoimmune condition had a lower incidence of oxalate crystals, especially in their inflamed thyroid gland areas. The study authors concluded that oxalates could play a role in the disorder by causing inflammation that triggers the autoimmune response, resulting in the destruction of both the oxalate crystals and thyroid tissue.

According to Dr. Wentz, oxalate sensitivity should be suspected if you have these symptoms and a thyroid condition like Hashimoto’s or Graves.

Joint pain

General body pain

Burning urination

Burning stools

Symptoms of intestinal permeability (leaky gut)

Depression

Kidney stones

Your doctor can order a test for oxalate build up here.

I wasn’t living in a country where we could get any kind of oxalate testing so I just went ahead and did a modified low histamine diet combined with a low oxalate diet. You can read how I did it and find my food list for that particular adventure in my post The Low Oxalate Low Histamine Diet: The Missing Link?. Many of my more recent recipes like in the Man Food book are low oxalate and I have the Low Oxalate Cookbook which was my first foray into that world.

The best resource to find more information on the Hashimoto’s oxalate link seems to be Dr. Wentz’s website (that I’m aware of).

It’s finally here! Man Food – a high nutrient antihistamine and anti-inflammatory ingredient filled book geared towards guys, women who love to work out, yoga like they mean it, or just load up on healing nutrients. Features my personal shopping list of antihistamine and anti-inflammatory foods.

The Anti-cookbook and all liquid Anti-Detox Book, don’t treat any conditions, but feature a plethora of the high nutrient antihistamine and anti-inflammatory ingredients that have been instrumental in helping me feed myself on a limited diet. The Anti-cookbook features a four page list of antihistamine and anti-inflammatory foods and comes in regular and Paleo.

The Low Oxalate Cookbook features antihistamine and anti-inflammatory rich recipes.

Don’t miss the Low Histamine Beauty Survival Guide for non-toxic beauty tips, the skinny on histamine releasing (mast cell degranulating) beauty ingredients, antihistamine and anti-inflammatory beauty alternatives and the top brands natural brands I’ve found.

Take a peek at my other low histamine and antihistamine cookbooks for more high nutrient recipes

talkhealth Blog

Fight histamine inflammation: live longer and younger

Inflammaging is the ageing effect of inflammation on the body and brain. We have modern medicine to thank for life span increases, but scientists believe part of the reason inflammation takes such a toll on us is because the immune system must nowadays stay active for longer than ever. This very long activity may lead to chronic inflammation that begins damaging internal organs. As a key component of the immune system, excess histamine is also implicated in ageing and damage to internal organs. Below you’ll find a list of natural anti-inflammatory foods and anti-ageing (all low histamine) oils for topical application. 

Alzheimer’s, diabetes and cancer all have an inflammatory component, but science tells us that genetics plays an important role in their development. Those with genes linked to inflammatory changes are “related to unsuccessful ageing”.

Inflammatory responses are believed to be the driving force behind tissue damage associated with age related diseases, which is why the term “inflammaging” was coined.

Chronic inflammation is considered to be involved in all age-related diseases.

Cancer rates spike dramatically in those 65 and over. Researchers are finding that previous infections in youth, which have triggered inflammation when fought, is a key measure of later inflammaging and cancer rates.

Lower rates of alzheimer’s disease in those with a history of long term use of NSAIDs like aspirin and ibuprofen, is another indicator of just how strongly inflammation impacts the ageing process.

A recent study of Japanese people over 100 years old found that, contrary to what we’ve been told in recent years, the best predictor of a long and healthy life is not telomere length, but levels of inflammation in the body. Scientists running the study found that lower levels of inflammatory agents released by mast cells in the blood meant longer life. The more mast cell activated inflammation in the body, the more age related disease and and shorter life expectancy.

In terms of skin, inflammation can accelerate fine lines, wrinkles, as well as causing engaged pores, puffiness, sagging, blotchiness and reddening of the skin.

One of the main keys to fighting inflammation is avoiding unhealthy fats like partially hydrogenated ones found in processed foods, cottonseed, palm, soy and corn oils, which can now even be found in “healthy” foods found on organic supermarket shelves. Eating anti-inflammatory foods, particularly ones rich in omega 3 fatty acids meanwhile has a significant anti-ageing effect on the body and brain.

One of the most terrifying symptoms of histamine/mast cell activated inflammation has to be its effect on the brain, otherwise known as brain fog. In my case this manifested in the inability to understand or remember what was being said in classrooms. I relied heavily on my notes, when I wasn’t too exhausted or disinterested to write them (motivation takes a plunge into the toilet bowl when you’re too tired to walk to class), but even a hint of stress would send said information scurrying into the furthest recess of my memory. A leftover from those years, which has sadly persisted to this day, is that I will question something I believe I know – something I have read or studied, simply because accessing memories formed in those troubled years is like trying to scoop up a catfish from a slimy green pond using freshly vaseline-d hands. The harder I try to extract said nugget of information from that murky green pond, the more it writhes and wriggles free, till I lose it, unsure it was ever there.

Thank goodness for iphones, wikipedia and google.

Luckily, memories formed in recent years have proven far easier to access (now that my brain fog has resolved) and so today I’m sharing some of the causes of brain fog in histamine disorders and the research on how to alleviate it. There is of course far more than just one cause and more than one approach to treating it.

According to a paper by Dr. Theoharides at Tufts, published in Neuropharmacology, a section of the journal Frontiers in Neuroscience, brain fog is a constellation of symptoms that include reduced cognition, inability to concentrate and multitask, as well as a loss of short and long term memory. The paper goes on to share that brain fog is common to those with celiac, chronic fatigue, autism spectrum disorders, fibromyalgia, mastocytosis, postural tachycardia syndrome, as well as in early clinical presentations of alzheimer’s. Dr. Theoharides believes that brain fog may be due to inflammatory molecules and histamine released from mast cells, causing brain inflammation.

The paper sums up the findings I spoke about earlier regarding histamine’s opposing roles in memory: “It appears that some histamine is necessary for alertness, learning and motivation, but too much histamine shuts the system down, in mast cells and histaminergic neurons, by activating H3 auto inhibitory receptors leading to brain “fog”.

The paper concludes with a review of recent research, including that of Dr. Theoharides, showing that flavonoids occurring in nature, like luteolin (though quercetin is also one), can prevent and treat neuropsychiatric and neurodegenerative diseases (including alzheimer’s). In a similar vein, researchers at the University of Illinois recently published research on how luteolin could help alleviate or prevent symptoms of alzheimer’s and multiple sclerosis, based on its brain protecting activity.

Now while we’re told that eating our medicine is unlikely to be enough for us, I still believe that eating a diet solely comprised of said healing foods is still an awesome healing approach, whether or not we choose to use supplements. I actually only came up with my diet after doing some hardcore research into mast cell stablising and histamine lowering nutrients available in the supermarket.

Common inflammation triggers

Excess histamine

Allergies

Stress

Trauma/injury

Inflammatory diet (high histamine diet, a diet low in omega 3 fatty acids, a diet high in processed foods)

Why take NSAIDs for inflammation when you can eat your medicine?

Studies show that NSAIDs delay muscle regeneration (like after you exercise), reduce cartilage healing, and others find that they work no better than placebos in reducing pain and soft-tissue swelling. This class of medications is also known to cause kidney damage and heart attack in older patients.

Please do not add any supplements to your diet without consulting your doctor. Sone of these supplements may be very high in salicylic acid and are not suitable for those with salicylate intolerance. 

Fish/omega 3 oils

Now recommended by the American Heart Association, fish oil is an important component of an anti-inflammatory diet. From a histamine perspective, it’s not so clear. The best choice would be an unfermented fish oil. Studies have found that DHA, a type of vegan omega 3 rich oil, is particularly effective at preventing histamine release from cells in animals.

I use Dr. Fuhrman’s DHA+EPA Purity oil with no problem.

White willow bark

One of the oldest inflammation remedies known to man, this tree bark is high in salicylic acid, the stuff aspirin is made of. It blocks the COX enzymes and prostaglandins. Studies show it can be as effective as NSAIDs and aspirin, with fewer side effects.

Curcumin

The active constituent of turmeric has been shown to be a potent anti-inflammatory with potential to treat colitis, neurodegenerative diseases, arthritis and cancer. It is also an antihistamine and mast cell stabiliser. It can however negatively impact the histamine-degrading enzyme DAO in some. I use turmeric daily in cooking.

Green tea

Anti-inflammatory, antihistamine and mast cell stabilising. As with all teas however, it may negatively impact the DAO enzyme. I drink green tea infrequently because of the caffeine.

Pycnogenol

Another bark product, this extract is comparable in efficacy to sodium cromolyn, the most commonly prescribed pharmaceutical for preventing histamine release from mast cells. It’s considered useful in promoting wound and ulcer healing in particular but also other inflammatory conditions.
Anti-inflammatory and antihistamine beauty/ageing prevention (to be applied topically)

Pomegranate seed oil

Baobab oil

Moringa oil

Oat masks

Coconut oil

——REFERENCES——

Bost, Jeffreyw, Adara Maroon, and Josephc Maroon. “Natural Anti-inflammatory Agents for Pain Relief.” Surgical Neurology International Surg Neurol Int 1.1 (2010): 80. Web.

Yamada, Koji, Mitsuo Mori, Noritaka Matsuo, Kentaro Shoji, Takashi Ueyama, and Michihiro Sugano. “Effects of Fatty Acids on Accumulation and Secretion of Histamine in RBL-2H3 Cells and Leukotriene Release from Peritoneal Exudate Cells Isolated from Wistar Rats.” Journal of Nutritional Science and Vitaminology, J Nutr Sci Vitaminol Journal of Nutritional Science and Vitaminology 42.4 (1996): 301-11. Web.

Franceschi, C., and J. Campisi. “Chronic Inflammation (Inflammaging) and Its Potential Contribution to Age-Associated Diseases.” The Journals of Gerontology Series A: Biological Sciences and Medical Sciences 69.Suppl 1 (2014): n. pag. Web.

“Brain Fog – the Histamine Connection and beyond.” THE LOW HISTAMINE CHEF. N.p., 2015. Web. 06 Aug. 2016.

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