Learn about different types of psoriasis in their mild to moderate forms. We include information on symptoms and treatment options for different types.
Eczema / Psoriasis News From Medical News Today
Tag Archives: Psoriasis
How to prevent psoriasis from spreading
A look at how psoriasis can spread. Included is detail on triggers for outbreaks, ways spread can be prevented, and risk factors for the condition.
Eczema / Psoriasis News From Medical News Today
Herpes zoster rates stay steady with biologics in psoriasis
Study shows no significant difference in herpes zoster risk between psoriasis patients receiving systemic therapy and those not receiving systemic therapy.
Dermatology Times – Dermatology
The top 25 psoriasis authors
In 2018 at just five days into the New Year, a search of PubMed revealed 86 new psoriasis studies. So, who is leading the pack?
Dermatology Times – Dermatology
Diet and lifestyle factors may trigger psoriasis
Environmental and lifestyle factors, such as certain foods and infections, may trigger onset of psoriasis and account for approximately 30% of the risk of the condition in people with a genetic preposition, research presented in London shows.
Dermatology Times – Dermatology
Directed evolution applied in the development of Psoriasis medications
Main category: Eczema / Psoriasis
Article Date: 22 March 2013-0:00 PDT current ratings for:
Directed evolution applied in the development of Psoriasis medications
University Ben-Gurion of researchers of the Negev (BGU), in collaboration with Teva Pharmaceutical Industries Ltd., have developed a promising drug candidate to treat psoriasis. The discovery was reported in a new paper published in chemistry and biology.
Psoriasis is a chronic, non-contagious disease characterized by covered flaming silver white crusting lesions of dead skin. An autoimmune disease, psoriasis affects at least 4 million Americans. It is caused by disturbances in the natural balance between proinflammatory and signals that inhibit inflammation.
One of the main signals involved in the progression of psoriasis is the protein of the immune system interleukin 17 (IL-17). The research team has developed a method for inhibiting pro-inflammatory signals IL-17 and proved that their engineered receptors, it-17R, is very effective in the reduction of inflammatory signals IL-17 induced in mouse models. Moreover, the injection of the receiver in a model mice with acute human psoriasis eliminated symptoms, mainly to cure this disease.
“Use of directed evolution to improve the properties of IL-17 receptor, we created engineered mutants which could prove it has a viable treatment for patients with severe psoriasis who do not respond to current drugs,” explains Dr. Amir Aharoni, one of the investigators of BGU Department of Sciences of life and the National Institute of biotechnology in the Negev.
“Given that the directed evolution method can be applied to other receptors involved in autoimmune diseases and cancer, I believe that we begin just to drill the potential of this approach,” adds Aharoni.
Directedhttp://www.eczemablog.net/ evolution is an iterative process of Darwinian optimization used in protein engineering whereby the fittest variants are selected from a collection of random mutations. Improved variants are identified and isolated by screening or selection for the property of interest. This approach is particularly advantageous in cases where no knowledge of the mechanism and the structure of the protein is available.
Article adapted by Medical News Today press release original. Click on “references” tab above for the source.Visit our eczema / psoriasis section for the latest news on this subject. Other researchers credited ‘Directed Evolution of a receptor Soluble de IL-17 human a for the Inhibition of the Formation of plaques of Psoriasis’ in a Murine model are BGU Dr. Marianna Zaretsky and Teva researchers Dr. Liora Sklair-Tavron, Dr. Joel Kaye, Revital Etzyoni.
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Eczema Blog
Cardiovascular disease in psoriasis may be due to a cardiosplenic axis
The spleen may have a role in driving the higher rate of cardiovascular disease seen in psoriasis patients through a spleen–atherosclerotic axis, suggests research presented at a meeting in London.
Dermatology Times – Dermatology
Impaired taste and smell may explain poor nutrition in psoriasis patients
Psoriasis has long been linked with poor nutrition, high body mass index and metabolic disorders. New research suggests a reduced sense of taste and smell, caused by inflammation, may explain why.
Dermatology Times – Dermatology
Psoriasis patient point of view
Almost two-thirds of patients with psoriasis have never gone into remission, shows a survey conducted by the health advocacy group Health Union.
Dermatology Times – Dermatology
Psoriasis Gene to Clinic Congress Highlights
Experts from around the world will gather in London at the Psoriasis from Gene to Clinic Congress to present and discuss the most current developments in the understanding of psoriasis and the evidence that will steer future clinical decision making. Watch here for highlights.
Modern medicine – dermatology