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How to spot the signs of bladder cancer and what to do next

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Bladder Cancer

A little guide for you this Bladder Cancer Awareness Month, from The Urology Foundation.

In the UK, there are over 10,000 new cases of bladder cancer diagnosed every year and nearly 5,000 people die from the disease each year. It affects men more than women, meaning that it is the fourth most common cancer in men and 12th most common in women.

How to know if you might have bladder cancer

Below are some signs that could indicate bladder cancer.

  • Blood in your urine: this is the most common symptom of bladder cancer. It won’t necessarily happen every time you pee and can sometimes disappear for weeks or months. You should look out for pee that looks anywhere from rusty to deep red.
  • Pain or burning when peeing: don’t panic if this happens to you quite rarely; it could just be because you haven’t drunk enough and your urine hasn’t been diluted enough. However, if this is a regular problem for you, that’s when you have cause for concern.
  • An increased need to urinate: if you find yourself going to the bathroom a lot more than you used to, this could be another indication of bladder cancer
  • Feeling the need to pee, but without anything coming through: another indication would be that you desperately need to use the toilet, but when you go, nothing happens

Each of these symptoms could indicate bladder cancer, but please don’t panic, as these could also be symptoms for a variety of other medical conditions.

What you should do next 

Because these symptoms could mean a variety of problems, it’s important that you don’t perform a self-diagnosis. Your next step should be to see your GP.

Your GP will conduct a variety of tests that could include a urine test, a blood test, and a physical examination of your stomach and your pelvis (this might include the vagina in women, and the rectum in men).

Your GP will use these results to decide whether you should be referred to a urologist, where you’ll be able to get the treatment you need.

If you’d like to read more about bladder cancer, take a look at our Bladder Cancer page.

If you’d like to keep in touch with The Urology Foundation about urology health, you can do that right here.

The post How to spot the signs of bladder cancer and what to do next appeared first on talkhealth Blog.

talkhealth Blog

Street Signs – Nametags For the Open Road

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Street signs are the name tags of the asphalt world. Used to provide the name of the stretch of road that you are on, they are the basis for all directions and addresses in the modern world. Typically found at intersections, atop tall poles, the street sign is one of the most common traffic signs in the world. Prior to the 1900’s bridges and buildings were used to identify the street that they were on. You would easily find a sign posted on a building or cornerstone that was chiseled with the name of the street on it. As more and more roads popped up however, and travel from one’s hometown became more common, a need for signs in places without buildings or bridges emerged, and thus the street sign was born.

Street signs are available in a variety of color combinations, ranging from the most common green with white reflective writing, to red and white, white and black and more. Some municipalities use uniquely colored street signs to distinguish them from other neighboring towns. Some private communities will have custom palettes and designs created to add to the ambiance of their neighborhood. Regardless of what they look like though, the purpose and function is the same – to help people to know where they are.

It was not until the 1900’s that street signs started popping up on utility poles and other poles designed expressly for the purpose of holding the street sign. Most intersections that post a street sign will have two signs mounted one atop the other and set perpendicular to one another, identifying both streets that are crossing. At modern, large intersections that have a traffic signal overhead, these signs are often much larger and hung from the wires or beams that the lights themselves are installed on. These larger signs are much more visible, making it much easier to navigate quickly through busy downtown areas.

Custom street signs are often ordered by businesses or individuals that are looking to place an identification on their own private roads. Although these signs may not actually denote a road that can be found on any map, they still mark off the street, allowing visitors to easily determine that they are at “Kim and Mark Place”. For all the best in street signage needs, visit Champion America today at http://www.champion-america.com With many color options available, you can design and order street signs that will meet your needs quickly and easily.

Ten signs of an eczema family

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There are a few ways I can now sleuth-out an eczema family at school, before I see any tell-tale physical signs.

This is just a bit of fun really, but got me thinking about what else I could add.  Please do add yours to the list too?Spotting fellow eczema families - they don't wear man made fibres. An image of a sock

  • EVERY single label has been cut out of your children’s clothing.
  • You only wear natural fibres – you’ve spent hundreds of hours searching for 100% cotton socks!
  • You ask for your child to be sat away from the radiator in winter and away from the open window in summer.
  • Your bathroom is stacked full of tubs of cream.
  • Even the word ‘summer’ fills you with dread.
  • Your fridge is full of oat milk, rice milk, coconut milk….anything but dairy.
  • You know how to say nuts/eggs/dairy in ten different languages.
  • You carry a HUGE bag around everywhere – epipen, antihistamine, eczema balm –  tick.
  • You can hear your child scratching through three rooms with all the doors shut.
  • Steam comes out of your ears when you’re asked for the tenth time that day if you’ve ever tried goat’s milk.

 

Everything For Eczema

Novartis Data Show AIN457 Significantly Reduced Signs And Symptoms In Patients With Hard-To-Treat Moderate-To-Severe Plaque Psoriasis

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AppId is over the quota AppId is over the quota Article adapted by Medical News Today from original press release. Click ‘references’ tab above for source.
Visit our eczema / psoriasis section for the latest news on this subject. 1. Paul C, Mroweitz U, Nakayama J et al. Secukinumab, a fully human, anti-interleukin (IL)-17A monoclonal antibody improves signs and symptoms of hand and foot psoriasis: results from a phase II regimen-finding trial. Presented at: 21st Congress of the European Academy of Dermatology and Venereology; 27-30 September, 2012; Prague, Czech Republic. Poster PRA12-0816.

2. Gaffen SL. Structure and signaling in the IL-17 receptor family. Nat Rev Immunol. 2009;9(8):556-67.


3. Ivanov S, Linden A. Interleukin-17 as a drug target in human disease. Trends Pharmacol Sci. 2009;30(2):95-103.


4. Kopf M, Bachmann MF, Marsland BJ. Averting inflammation by targeting the cytokine environment. Nat Rev Drug Discov. 2010;9(9):703-18.


5. Radtke MA, Langenbruch AK, Schafer I et al. Nail psoriasis as a severity indicator: results from the PsoReal study. Patient Relat Outcome Meas. http://www.eczemablog.net/ 2011;2:1-6


6. Pettey AA, Balkrishnan R, Rapp et al. Patients with palmoplantar psoriasis have more physical disability and discomfort than patients with other forms of psoriasis: implications for clinical practice. J Am Acad Dermatol. 2003;49(2) :271-275.


7. Gottlieb AB, Reich K, Philipp S et al. Secukinumab improves signs and symptoms of nail psoriasis: results from a phase II regimen-finding trial. Presented at: 21st Congress of the European Academy of Dermatology and Venereology; 27-30 September, 2012; Prague, Czech Republic. Poster PRA12-0668.


8. Wilsmann-Theis D, Terui T, Draelos Z et al. Improvement with secukinumab on patient reported skin related quality of life (QoL) and health status among moderate-to-severe plaque psoriasis patients: results from a phase II regimen-finding trial. Presented at: 21st Congress of the European Academy of Dermatology and Venereology; 27-30 September, 2012; Prague, Czech Republic. Poster: PRA12-0822.


9. Rapp SR, Feldman SR, Exum, ML et al. Psoriasis causes as much disability as other major medical diseases. J Am Acad Dermatol. 1999;41(3):401-407.Leipe J, Grunke M, Dechant C et al. Role of Th17 cells in human autoimmune arthritis. Arthritis Rheum. 2010;62:2876-2885.


10. Rich P.A. et al. Secukinumab, a new fully human monoclonal anti-Interleukin-17A antibody, in the treatment of moderate-to-severe plaque psoriasis: Interim efficacy and safety data from a phase II regimen-finding trial. Presented at: 20th Congress of the European Academy of Dermatology and Venereology; 20-24 October, 2011; Lisbon, Portugal. Oral presentation FC01.6.


11. Genovese M, Kellner H, Durez P, et al. Secukinumab treatment improves ACR50, HAQ-DI and EULAR remission rates in patients with rheumatoid arthritis. At: EULAR 2012, The Annual European Congress of Rheumatology; 6-9 June 2012, Berlin, Germany. Abstract 2925.


12. Baeten D, Sieper J, Emery P, et al. The anti-il17a monoclonal antibody secukinumab (AIN457) showed good safety and efficacy in the treatment of active ankylosing spondylitis. At: EULAR 2011, The Annual European Congress of Rheumatology, 25-28 May 2011, London, UK. Abstract 0174.


13. McInnes I, Sieper J, Braun J, et al. Anti-Interleukin 17A monoclonal antibody secukinumab reduces signs and symptoms of psoriatic arthritis in a 24-week multicenter, double-blind, randomized, placebo- controlled trial. Presented at: Annual Scientific Meeting of the American College of Rheumatology/Association of Rheumatology Health Professionals; 4-9 November 2011; Chicago, IL. Abstract 19541.


14. Raychaudhuri SP, Farber EM. The prevalence of psoriasis in the world. J Eur Acad Dermatol Venereol. 2001;15:16–17.


15. Nestle FO, Kaplan DH, Barker J. Psoriasis. N Engl J Med 2009;361:496-509.


16. Herrier R. Advances in the treatment of moderate-to-severe plaque psoriasis. Am J Health-Syst Pharm 2011;68:795-806.


17. Farley E, Masrour S, McKey J et al. Palmoplantar psoriasis: a phenotypical and clinical review with introduction of a new quality-of-life assessment tool. J Am Acad Dermatol. 2009;60(6):1024-1031.


Disclaimer


The foregoing release contains forward-looking statements that can be identified by terminology such as “promising,” “on track,” “expected,” “encouraging,” “may,” “look forward to,” “to follow,” or similar expressions, or by express or implied discussions regarding potential marketing submissions or approvals for AIN457, or the timing of any such submissions or approvals, or regarding potential future revenues from AIN457. You should not place undue reliance on these statements. Such forward-looking statements reflect the current views of management regarding future events, and involve known and unknown risks, uncertainties and other factors that may cause actual results with AIN457 to be materially different from any future results, performance or achievements expressed or implied by such statements. There can be no guarantee that AIN457 will be submitted or approved for approval in any market, or at any particular time. Nor can there be any guarantee that AIN457 will achieve any particular levels of revenue in the future. In particular, management’s expectations regarding AIN457 could be affected by, among other things, unexpected clinical trial results, including unexpected new clinical data and unexpected additional analysis of existing clinical data; unexpected regulatory actions or delays or government regulation generally; competition in general; government, industry and general public pricing pressures; the company’s ability to obtain or maintain patent or other proprietary intellectual property protection; unexpected manufacturing issues; the impact that the foregoing factors could have on the values attributed to the Novartis Group’s assets and liabilities as recorded in the Group’s consolidated balance sheet, and other risks and factors referred to in Novartis AG’s current Form 20-F on file with the US Securities and Exchange Commission. Should one or more of these risks or uncertainties materialize, or should underlying assumptions prove incorrect, actual results may vary materially from those anticipated, believed, estimated or expected. Novartis is providing the information in this press release as of this date and does not undertake any obligation to update any forward-looking statements contained in this press release as a result of new information, future events or otherwise.

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UK, Burson-Marsteller. “Novartis Data Show AIN457 Significantly Reduced Signs And Symptoms In Patients With Hard-To-Treat Moderate-To-Severe Plaque Psoriasis.” Medical News Today. MediLexicon, Intl., 1 Oct. 2012. Web.
7 Apr. 2013. APA

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Eczema Blog

Eczema Rashes, Signs And Symptoms

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Eczema may refer to any of several skin disorders, which is characterized by inflamed Eczema rashes and itchy skin. It is usually accompanied by crusting, flaking and dryness. Those with advanced symptoms may also experience oozing, weeping, skin edema, blistering and cracking. Despite its varying symptoms, Eczema generally affects the upper layer of the skin or “dermis”, hence, the term dermatitis.
Eczema and dermatitis have some similarities, but they are actually 2 different skin disorders. They are both common complaints and are often interchanged. Dermatitis refers to inflammation of the skin, while Eczema is coined from a Greek term that means “boiling”. A person who has Eczema may experience sore and itchy Eczema rashes, as a result of a combination of chemicals and antibodies that are present on our skin.
There are several ways to classify Eczema rashes, depending on the person’s perspective. It can be distinguished based on the affected area. Dyshidrotic Eczema, for instance, refers to rashes that are found on the hands or feet. It can also be based on the source of Eczema, like varicose Eczema. Discoid Eczema got its name from the coin-like appearance of rashes. It is also known as nummular Eczema.
Regardless of its many forms, Eczema is still characterized by red and inflamed rashes, and itchy skin. Atopic dermatitis is one of the most common types of Eczema, and is believed by medical professionals to be hereditary. Contact dermatitis, on the other hand, is caused by external aggravating factors like chemicals and contact allergens. Baby Eczema rashes are often mistaken for seborrheic dermatitis. It is more commonly known as cradle cap.
It can be very confusing to determine the type of Eczema rashes that you have. Nonetheless, proper diagnosis is important to ensure appropriate care and treatment. Learning the various types of Eczema will help you distinguish each type from the others. This is extremely crucial in determining the proper course of treatment and handling.

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