Melatonin Might Help Sleepless Kids With Eczema, Study Finds
Eczema, also called atopic dermatitis, is characterized by an itchy, red rash. It affects as many as 30 percent of all kids, more than half of whom experience sleep difficulties, the researchers said. These sleep problems can be difficult to treat in …
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Study On Mice Reveals Cause Of Itch In Eczema, Hints Possible Treatment
Study On Mice Reveals Cause Of Itch In Eczema, Hints Possible Treatment
According to the National Eczema Association, there is no cure for eczema but it is manageable. Children who have this condition might outgrow it when they become adults while others suffer from it until adulthood. Around one out of three children …
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More eczema cases seen in hospitals
Eczema is also the top skin condition treated at National University Hospital (NUH) and National Skin Centre, which has seen more children under the age of five with it, said consultant Madeline Ho. The disease commonly starts in childhood and often …
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Mouse Study Hints at Treatment for Itch-Related Ills Like Eczema
Mouse Study Hints at Treatment for Itch-Related Ills Like Eczema
THURSDAY, June 11, 2015 (HealthDay News) — An itch that just won't go away: Many people will suffer from eczema or some other ailment involving chronic itch during their lifetime, and a new study in mice hints at why this happens. The scientists who …
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Northeast Tarrant sees boom in wellness-focused businesses
Opened in August, the Salt Cave's clients regularly come in to find relief from rheumatoid arthritis and autoimmune disease symptoms as well as migraines, skin issues like eczema and even anxiety. Sessions are $ 45 and last one hour, but discounted …
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AAAAI: Study Shows Peanut in House Dust Linked to Peanut Allergies, Especially for Children Prone to Eczema
Milwaukee, WI (PRWEB) November 18, 2014
According to a new study, led by King’s College in London, infants who have impaired skin barriers and are exposed to peanut proteins – which can be found in household dust – are more likely to develop sensitivities to peanuts.
The article was published on November 18 in The Journal of Allergy and Clinical Immunology (JACI), an official journal of the American Academy of Allergy, Asthma & Immunology (AAAAI).
“Our findings point to a biological plausibility that environmental peanut exposure might be sensitizing children through an impaired skin barrier,” first author Helen Brough, MA (Hons), MSc, MBBS, FRCPCH, explained in the study.
The study examined the amount of peanut proteins which 359 infants, from a high-risk cohort, were exposed to by vacuuming and analyzing household dust found on the living room floor. Peanut-based food can leave peanut proteins behind in household dust, even after regular cleaning.
The children, aged 3-15 months, were considered to be at a high risk of developing peanut allergy because they were either allergic to cow’s milk or egg and/or prone to eczema. In this study, researchers found that exposure to dust with peanut proteins doubled the risk of peanut allergy. Children with a history of eczema were at greater risk.
“The effect of peanut dust exposure on peanut sensitization is augmented in children with a history of atopic dermatitis (eczema) and even further in children with a history of severe eczema,” according to senior author Gideon Lack, MD.
The study calls for further research to examine what’s being coined as dual-allergen-exposure theory, that is, testing the idea that while exposure to allergens through the skin can create sensitivities, perhaps consumption of these food proteins early in life can build a tolerance in the body. Regardless, reducing the environmental exposure to food allergens could be explored to prevent the development of food sensitization and food allergies.
“It may be that the timing and balance of skin and oral exposure to a particular food, early in life, especially for atopic children, could determine whether a child develops an allergy or tolerance to that food,” collaborating author Scott Sicherer, MD, FAAAAI, from Jaffe Food Allergy Institute & Icahn School of Medicine at Mount Sinai explained.
More information on food allergies and eczema is available at the AAAAI website. The full study was performed in collaboration with the NIH/NIAID funded Consortium for Food Allergy Research (CoFAR) and can be accessed through the JACI.
The AAAAI represents allergists, asthma specialists, clinical immunologists, allied health professionals and others with a special interest in the research and treatment of allergic and immunologic diseases. Established in 1943, the AAAAI has more than 6,800 members in the United States, Canada and 72 other countries. The AAAAI’s Find an Allergist/Immunologist service is a trusted resource to help you find a specialist close to home.
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Landmark study presented at AAAAI Annual Meeting paves way for food allergy prevention
Houston, TX (PRWEB) February 23, 2015
The first ever published data from the highly anticipated Learning Early About Peanut (LEAP) study offers proof that early introduction of peanuts may offer protection from the development of peanut allergies. The study was led by Professor Gideon Lack at King’s College London.
“We believe the results from this trial are so compelling, and the problem of the increasing prevalence of peanut allergy so alarming that new guidelines should be forthcoming very soon,” Hugh A. Sampson, MD, FAAAAI, noted in an accompanying editorial. Sampson is a past-president of AAAAI and current Director of the Jaffe Food Allergy Institute with the Icahn School of Medicine at Mount Sinai.
Lack and the LEAP study team randomly assigned 640 infants with severe eczema, egg allergy, or both, to either consume or avoid peanuts until 60 months of age. Additional clusters were identified in the cohort: children with sensitivity to peanut extract and children without sensitivity (as determined by skin prick tests).
Remarkably, the overall prevalence of peanut allergy in the peanut-avoidance group was 17.2% compared to only 3.2% in the consumption group. The prevalence of peanut allergies in children with negative skin prick tests early in life was at 13.7% in the avoidance group and 1.9% in the consumption group. Similarly, children already sensitive to peanuts reflected a 35.3% prevalence of peanut allergy in the avoidance group, compared to only 10.6% in the consumption group.
“Early consumption is effective not only in high-risk infants who show no sensitivity to peanuts early on, but it is also effective in infants who already demonstrate peanut sensitivity,” first author George Du Toit, MB, BCh, also from Kings College London explained.
While additional questions remain, researchers now wonder if the LEAP study – which has demonstrated that the early introduction of peanut dramatically decreases the risk of developing a peanut allergy by a staggering 70-80% – should prompt a change in food allergy guidelines.
“There appears to be a narrow window of opportunity to prevent peanut allergy,” says Lack. “As soon as infants develop the first signs of eczema or egg allergy in the first months of life, they should receive skin testing to peanut and then eat peanut products either at home if the test is negative or first under clinical supervision if the test if positive. Infants without such symptoms should be fed peanut products from four months of life.”
Lack added that this advice applies to children in countries where peanut allergy is a problem and cautions that infants should not be fed whole peanuts because of the risk of choking.
The “Randomized Trial of Peanut Consumption in Infants at Risk for Peanut Allergy” was published in The New England Journal of Medicine and presented at a Keynote address for the American Academy of Allergy, Asthma & Immunology (AAAAI) Annual Meeting in Houston. Funding for the LEAP study was provided by the National Institute of Allergy and Infectious Diseases (NIAID) and Food Allergy Research & Education (FARE).
More information on peanut allergies and the Annual Meeting is available at the AAAAI website.
The AAAAI represents allergists, asthma specialists, clinical immunologists, allied health professionals and others with a special interest in the research and treatment of allergic and immunologic diseases. Established in 1943, the AAAAI has more than 6,800 members in the United States, Canada and 72 other countries. The AAAAI’s Find an Allergist/Immunologist service is a trusted resource to help you find a specialist close to home.
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